Trans Kids-Lupron/Lucrin and the DEADLY Effects of Hormone Blockers

Australia’s LGBTI Health Alliance welcomes the recent Family Court decision to allow a 13 year old transgender boy to receive Lucrin, a medication that suppresses the hormones responsible for physical changes during puberty. In other words, hormone blockers. In the Re: Lucy (Gender Dysphoria) [2013] FamCA 518 decision, the Family Court ruled that Court authorisation will no longer be required when trans young people request hormone-blocking medication.

The above is sited from this article which either ignorantly or deceptively claims that "The hormone-blocking effects of Lucrin are fully reversible". and "Studies show that Lucrin can be safely administered to young people for several years prior to full pubertal onset".

Before going further, so there is no confusion, Lupron is the US drug that has been conveniently renamed Lucrin in Australia.

Some possible side effects of Lupron:

Call your doctor at once if you have:

  • bone pain, loss of movement in any part of your body;
  • swelling, rapid weight gain;
  • pain, burning, stinging, bruising, or redness where the medication was injected;
  • feeling like you might pass out;
  • sudden chest pain or discomfort, wheezing, dry cough or hack;
  • painful or difficult urination;
  • urinating more often than usual;
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);
  • sudden numbness or weakness (especially on one side of the body), problems with speech or balance;
  • sudden headache with vision problems, vomiting, confusion, slow heart rate, weak pulse, fainting, or slow breathing; or
  • chest pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.
Rare but serious side effects may include:

  • pain or unusual sensations in your back;
  • numbness, weakness, or tingly feeling in your legs or feet;
  • muscle weakness or loss of use;
  • loss of bowel or bladder control; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:

  • acne, increased growth of facial hair;
  • breakthrough bleeding in a female child during the first 2 months of leuprolide treatment;
  • dizziness, weakness, tired feeling;
  • hot flashes, night sweats, chills, clammy skin;
  • nausea, diarrhea, constipation, stomach pain;
  • skin redness, itching, or scaling;
  • joint or muscle pain;
  • vaginal itching or discharge;
  • breast swelling or tenderness;
  • testicle pain;
  • impotence, loss of interest in sex;
  • depression, sleep problems (insomnia), memory problems; or
  • redness, burning, stinging, or pain where the shot was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

More on the life altering and life threatening dangers of Lupron/Lucrin and its fabricated research:

 And a bit from those suffering from the nightmare effects of this detrimental drug:

There is a current petition in US congress to get this dangerous drug removed from the market. There are pages and pages and pages of more detrimental testimonials from (mostly women and mother's of daughters) suffering the short and long term side effects from Lupron/Lucrin.

I suspect the homophobic trans kid angle is a last ditch effort by the maker's of Lupron/Lucrin to make more money from a drug whose end is near. But history tells us the wheels of justice are turtle slow, how many trans gay/lesbian children will have their lives permanently damaged or ended from this drug due to homophobic parents sweating over their kid playing with the wrong toy and an equally homophobic medical community ready, willing and able to make a buck off those fears?

But given transitional drugs with no long term studies and dangerous life threatening effects of their own coupled with brutal life damaging surgeries that coincide with transition, should we even be surprised at the loaded Lupron/Lucrin gun being aimed and fired at gay and lesbian children or children thought to be gay or lesbian, much in the way transition itself has?



  1. Please sign the petition. I read some of the complaints, and this is disturbing.

  2. 2,714 People Have Sent 5,345 Letters and Emails

    There are complaints about horrible side effects that go back to 2009.


    These children don't even have a medical condition, or medical rationale for taking Lupron. It's given to children by "gender therapists" or therapists who say six and seven year old children have "gender dysphoria".

  3. ysathra 15This chemical is not typically prescribed for children as no one knows what side effects may be long-term in children. Thank you for this detailed expose, Dirt.

    So little girls are being administered this poisonous stuff b4cause they don't gender-conform. I ask, who in the Trans community is speaking upfor the health of these little girls? Are they being sacrificed for some half-formed ideology? Shouldn't everybody take a step back, test this stuff?

  4. ALL medication has side effects ass hat!

  5. Are they being sacrificed for some half-formed ideology.

    Absolutely, this is exactly what is going on, but transgender activists are very skilled at shutting down any critical analysis, thought, or opinion that doesn't meet with their approval.

    ALL medication has side effects ass hat!

    Dear Mr. or Ms. Ass Hat:

    Everyone knows that all medications have side effects. People don't have to be doctors to know this. Since all medications have side effects, shouldn't people use extra caution and some common sense when it comes to children? Take time to read some of the comments about side effects. At least most of these people state that they had some kind of medical condition, and this is why they were prescribed Lupron. "Transgender" 12 or 13 year old children are physically no different than other children. It's a psychological diagnosis in children, and is subjective by its very nature.

    This assumes all the following:

    (a.) The diagnosis is correct to being with, and there isn't something else going on in the child's life.

    (b.) The child is completely free from any parental, peer, or cultural influences. How much is "gender dysphoria" in a 12 year old child, and how do we separate this from everything the parents read on transgender websites and blogs? How much is actual "gender dysphoria" or GID and how much is parental discomfort at having a child that doesn't fit neatly into sex based gender roles?

    (c.) Children have the mental capacity to decide or choose for themselves.

    It’s a scientific fact that the pre-frontal cortex of the human brain which is sometimes called the judgment center of the brain isn’t fully developed until the early to mid-twenties.

    ”The prefrontal cortex, the part of the frontal lobes lying just behind the forehead, is often referred to as the “CEO of the brain.” This brain region is responsible for cognitive analysis and abstract thought, and the moderation of “correct” behavior in social situations. The prefrontal cortex takes in information from all of the senses and orchestrates thoughts and actions to achieve specific goals.1,2 This brain region gives an individual the capacity to exercise “good judgment” when presented with difficult life situations. Brain research indicating that brain development is not complete until near the age of 25, refers specifically to the development of the prefrontal cortex.”

  6. This is what the transgender community won't admit. People are willing to jeopardize the health of children, even make them sterile essentially for cosmetic reasons. Whether they admit it or not, one of the major benefits of puberty suppressing drugs is that it makes later “transitioning” much easier. Since these children don’t go through normal adolescent development, there is less healthy tissue to surgically remove later. Also, these individuals are said to 'blend in better.' Boys don’t develop masculine characteristics, and girls get little, if any, breast development. So, the surgeon has less to remove later. They develop few physical characteristics of the sex they were born into. This is because they weren’t allowed to go through normal adolescent development to begin with, and then they receive cross gender hormones. This is why they pass so well. When we think about it, it seems so Orwellian to me that I have trouble even wrapping my mind around it.

    The transgender community and the clinics who give prescribe puberty suppressing drugs to children always say that they are reversible. This is only partially true and they know it. Depending on where you live, with parental approval, cross gender hormones can start at age 16. Some children go straight from puberty suppressing drugs to cross gender hormones.

    Treatment with puberty delaying drugs leads to sterilization if it is followed with the administration of cross sex hormones at 16 years, as the Brill and Pepper handbook on “transgender” children (2008), explains, “the choice to progress from GnRH inhibitors to estrogen without fully experiencing male puberty should be viewed as giving up one's fertility, and the family and child should be counseled accordingly” (Brill & Pepper, 2008, p. 216). For girls, sterilization is the outcome too, because “eggs do not mature until the body goes through puberty” (Brill & Pepper, 2008, p. 216). The issue of fertility, the handbook asserts, may bother parents more than the “teens”, because the latter may think shortterm and not be able to contemplate much more than getting transgendered in the present (Brill & Pepper, 2008, p. 220). The handbook speaks of other serious effects of the transgendering of children. It says that birth defects may occur in children born to “transmen taking testosterone prior to pregnancy” (Brill & Pepper, 2008, p. 219). It also warns that genital surgery can lead to the absence of sexual feeling, and comments that young people may not understand the importance of this (Brill & Pepper, 2008, p. 220). But, the handbook advises, “teens” can have sexual surgeries such as the removal of testes or breast removal, at any age, not necessarily 18, so long as their parents and a surgeon are willing (Brill & Pepper, 2008, p. 220). This does seem to contradict the warnings that accompany this advice, about the difficulty “teens” may have in understanding the implications of such surgeries for fertility and sexual pleasure.

    In addition to numerous complaints about side effects from adults who have taken Lupron, some doctors apparently are willing to jeopardize the future fertility of children. Sterilizing children comes with ethical issues, and it's often considered a human rights abuse.

  7. I'm not a doctor, but isn't it true that Lupron for "transgender" children is an off label use? Is it even approved by the FDA for this specific use?

    Lupron is prescribed for women with very bad endometriosis or severe menorrhagia. It also may be administered before assisted reproduction. In men, Lupron is used to treat advanced prostate cancer. It also may be used in children who are diagnosed with central precocious puberty (early puberty).

    Lupron® is a Gonadotropin-Releasing Hormone Analog/Agonist (GnRH); these drugs shut down the pituitary gland, thereby reducing the amount of testosterone produced by men, and estrogen produced by women.

    It's important to note that Lupron doesn't actually cure prostrate cancer or endometriosis. It shuts down the hormones that stimulate tumor growth or spur the growth of endometrial tissue.

    "This deprives hormone-dependent prostate cancer cells of the hormone (ie, testosterone) they need to grow, causing their growth to slow. Decreasing the amount of testosterone in the body can result in a reduction of symptoms related to advanced prostate cancer, such as bone pain or difficulty in urinating. It is important to remember that Lupron Depot is used for palliative treatment and is not a cure for cancer."

    "The FDA reports that, as long ago as 1999, it had received adverse drug reports about Lupron® from 4,228 women and 2,943 men.1 These side effects included: tingling, itching, headache and migraine, dizziness, severe joint pain, difficulty breathing, chest pain, nausea, depression, emotional instability, dimness of vision, fainting, weakness, amnesia, hypertension, muscular pain, bone pain, nausea/vomiting, asthma, abdominal pain, insomnia, chronic enlargement of the thyroid, liver function abnormality, vision abnormality, and anxiety, and others.2 In 325 of these cases, the women required hospitalization; 25 women died.3 At the time, the FDA said that it did not have enough staff capacity to assess any causal effect in these cases."

  8. The doctors defying the FDA by prescribing transgender kids with puberty-supressing drugs

    "While the medication is approved by the Food and Drug Administration for children who start puberty prematurely, it is currently unapproved for transgender adolescents.

    Only a small number of clinics in America serve transgender children, and it was only a few years ago that doctors began treating them with puberty-blocking drugs."

  9. Precocious puberty is NOT the same as transgender. Here is something from the Mayo Clinic website.

  10. Hypothalamus kicks out GnRH which the pituitary gland (the old master gland) uses to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.

    What they are doing is basically giving a drug used to treat central precocious puberty to "gender dysphoric" children.

    Lupron is not the only GnRH agonist drugs. Supprelin (histrelin acetate) is a GnRH agonist that is used for central precocious puberty (puberty when kids shouldn't normally go through puberty). It's an implant that is inserted in the arm. Completing puberty too early means the child may have fewer growth years. The kid may not reach his or her expected adult height.

    "For the majority of children with this condition, there's no underlying medical problem and no identifiable reason for the early puberty.

    In rare cases, the following may cause central precocious puberty:

    A tumor in the brain or spinal cord (central nervous system)
    A defect in the brain present at birth, such as excess fluid buildup (hydrocephalus) or a noncancerous tumor (hamartoma)
    Radiation to the brain or spinal cord
    Injury to the brain or spinal cord
    McCune-Albright syndrome — a genetic disease that affects bones and skin color and causes hormonal problems
    Congenital adrenal hyperplasia — a group of inherited disorders involving abnormal hormone production by the adrenal glands
    Hypothyroidism — a condition in which the thyroid gland doesn't produce enough hormones



    Brand Names: U.S.
    •Supprelin® LA

    Adverse Reactions


    >10%: Local: Insertion site reaction (51%; includes bruising, discomfort, itching, pain, protrusion of implant area, soreness, swelling, tingling)

    >2% to 10%:

    Endocrine & metabolic: Metrorrhagia (4%)

    Local: Keloid scar (6%), scar (6%), suture-related complication (6%), pain at the application site (4%), post procedural pain (4%)

    ≤2% (Limited to important or life-threatening): Amblyopia, breast tenderness, cold feeling, disease progression, dysmenorrhea, epistaxis, erythema, flu-like syndrome, gynecomastia, headache, infection at the implant site, menorrhagia, migraine, mood swings, pituitary adenoma, pituitary apoplexy, pruritus, seizures, weight gain.

    When used for treatment of central precious puberty, initial agonistic action of histrelin may cause transient increases in estradiol serum levels (female) or testosterone levels (female and male); typically during first week of therapy; worsening of symptoms or onset of new symptoms may occur during this time; however, manifestations of puberty should decrease within 4 weeks. Rare cases of pituitary apoplexy have been observed, frequently secondary to pituitary adenoma; reported onset from 1 hour to usually <2 weeks; may present as sudden headache, vomiting, visual or mental status changes, and infrequently cardiovascular collapse; immediate medical attention required if occurs.

  11. The problem with the petition is that taking it completely off the market would leave men with prostate cancer with no treatment option. So it should be changed to 'to be used only in medically necessary cases. Not wanting to experience puberty at the normal age range is definitely not medically necessary.

  12. The problem with the petition is that taking it completely off the market would leave men with prostate cancer with no treatment option. So it should be changed to 'to be used only in medically necessary cases. Not wanting to experience puberty at the normal age range is definitely not medically necessary.

    I agree and this is just common sense. Thank you for the comment.

    I'm not a doctor, but the thing about GnRH agonists is that they don't actually cure anything. In males, they suppress the production of testosterone that promotes prostate tumor growth. Below is a link form the FDA about possible side effects.

    "Most of the studies reviewed by FDA reported small, but statistically significant increased risks of diabetes and/or cardiovascular events in patients receiving GnRH agonists. FDA's review is ongoing and the agency has not made any conclusions about GnRH agonists and whether they increase the risk of diabetes and cardiovascular disease in patients receiving these medications for prostate cancer.

    Healthcare professionals and patients should be aware of these potential safety issues and carefully weigh the benefits and risks of GnRH agonists when determining treatment choices. FDA recommends that patients receiving GnRH agonists should be monitored for development of diabetes and cardiovascular disease. Patients should not stop their treatment with GnRH agonists unless told to do so by their healthcare professional.

    Some GnRH agonists are also used in women and in children for other indications than those above. There are no known comparable studies that have evaluated the risk of diabetes and heart disease in women and children taking GnRH agonists.

    In females, it is used to manage endometriosis because it suppresses hormones that stimulate endometrial tissue. After reading some of the complaints from women, some women say the side effects are horrible.

    As to precocious puberty, there is some interesting research that shows that children start puberty earlier than they did twenty or thirty years ago. Some chemicals mimic hormones. Instead of looking for toxins and environmental factors and eliminating these things, it's easier and more profitable to give children drugs.

    All I can say is consult a doctor and do your own research.

  13. Why does the Endocrine Society support puberty suppressing drugs for a dubious psychological diagnosis in children? It's so strange to me how endocrinology ever got involved in psychiatry.

    It goes like this. Create the demand then expect to reap the profits. I've thought about this, and this is my opinion. It's about creating a demand then filling it. Think $$. Think about this carefully. Endocrinology isn't exactly the most lucrative medical specialty, and this is one way for them to make more money by going along with a socially prescribed cure for kids that just don't fit in. Look at what endocrinologists earn compared to other medical specialties like orthopedic surgeons or cardiologists.

    The 10 highest-paid specialists

    According to the report, the 10 highest-paid specialties last year were:

    1. Orthopedic surgery ($405,000)
    2. Cardiology ($357,000)
    3. Radiology ($349,000)
    4. Gastroenterology ($342,000)
    5. Urology ($340,000)
    6. Anesthesiology ($337,000)
    7. Plastic surgery ($317,000)
    8. Dermatology ($306,000)
    9. General surgery ($279,000)
    10. Oncology ($278,000)

    The 10 lowest-paid specialties

    Meanwhile, the 10 lowest-paid specialties last year were:

    1. HIV/infectious diseases ($170,000)
    2. Pediatrics ($173,000)
    3. Family medicine ($175,000)
    4. Diabetes/endocrinology ($178,000)
    5. Internal medicine ($185,000)
    6. Psychiatry ($186,000)
    7. Rheumatology ($186,000)
    8. Neurology ($217,000)
    9. Obstetrics/Gynecology ($242,000)
    10. Pathology ($247,000)

  14. Investigation into Lupron Side Effects (Leuprolide Acetate)

    As of 8/17,

    5,377 Letters and Emails Sent So Far

  15. The endocrinologists make money from prescribing Lupron and other GnRH agonists to children for what amounts to a questionable psychological diagnosis in kids. They inject the Lupron or implant the GnRH agonist Supprelin at the first sign of puberty, monitor the blood work to see how it's going (more $$), and then they start the kid out on cross gender hormones at age 16 which have to be taken for life (even more $$).

    ...$$$ for endocrinologists who generally as a medical specialty don't make a lot of money compared to surgeons, etc.

    ...creating a demand and filling it...

    Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline

    "1.3. We recommend that physicians evaluate and ensure that applicants understand the reversible and irreversible effects of hormone suppression (e.g.,GnRH analogue treatment) and cross-sex hormone treatment before they start hormone treatment."

    (***These are children, and how can we say that they are fully capable of making informed decisions and they have the judgment and maturity to weigh all their options. Should parents be the ones to decide the future fertility of their own children? Can parents sterilize their own children?)

    1.4. We recommend that all transsexual individuals be informed and counseled regarding options for fertility prior to initiation of puberty suppression in adolescents and prior to treatment with sex hormones of the desired sex in both adolescents and adults."

    (***Please note that they refer to children as "transsexual individuals". It appears that are at least admitting that GnRH agonists followed by cross gender hormones might effect future fertility in children.)

    2.1. We recommend that adolescents who fulfill eligibility and readiness criteria for gender
    reassignment initially undergo treatment to suppress pubertal development.
    2.2. We recommend that suppression of pubertal hormones start when girls and boys first exhibit physical changes of puberty(confirmed by pubertal
    levels of estradiol and testosterone, respectively,
    but no earlier than Tanner stages 2–3.(***$$ they test for this too)

    2.3. We recommend that GnRH analogues be used to achieve suppression of pubertal hormones.2.4. We suggest that pubertal development of the desired opposite sex be initiated at about the age of 16 years, using a gradually increasing dose schedule of cross-sex steroids."

  16. ??? Attention Dirt: please remove this August 14, 2013 at 3:21 PM
    post because it makes no sense. Perhaps this person copied and pasted the wrong thing.

    2,714 People Have Sent 5,345 Letters and Emails


    I think I understand what they did wrong. They copied and pasted the second or third page of the petition instead of going to the very first page. Silly mistake...they must have been in a hurry..

    August 14, 2013 at 3:21 PM


    ***According to the website,

    Investigation into Lupron Side Effects (Leuprolide Acetate)

    5,377 Letters and Emails Sent So Far

    "I took one 3 month shot in 2000 following a surgery to remove endometriosis. My life changed after that one shot. I left work for two weeks for surgery and was never able to go back full time. I was bed ridden for almost two months. I experienced bone pain, severe stomach pain, extreme weakness, migraines, and more. I initially lost 30 pounds within months, but later gained more than 60 and can not get the weigh off even following a very healthy diet. In time, I was diagnosed with a systemic disease, interstitial cystitis, pernicious anemia, corneal eye disease, and a brain tumor. Were they all connected to this drug? I don't know. I can only say Lupron Depot seemed to be the catalyst for the SUDDEN decline in my health. This drug should never be administered to anything living."

    "I was put on Lupron for Endometriosis in my bladder, 41 years old, I got 2 shots and missed the 3rd one because my insurance company told me that I was out of pocket and I considered that it was so expensive for me, soon after my first shot I got horrible hot flashes, back pain, suicidal thoughts, weight gain, I feel sick all the time, I got two flu viruses that lasted for 6 weeks, loss of memory, short of breath and I remember one of my visits to my ob-gyn the nurse asked me for my age and I've totally forgotten it, that happened to me on my first shot, now I can't even remember few things, names, songs, words, and things of my daily life. I blame myself because I never did a whole research about this drug and I trusted my gynecologist. My shots were given to me back in 2009-10. Since then I have had heavier periods, cramps, fatigue, eye pain, dry eyes, my back pain doesn't allow me to sleep at night, and from January 2013 to April my period didn't come, then it came on April 2013 and hasn't stop and my last blood test show some thyroid problems. Please don't take this medication, take this drug off the market. To Doctors all have daughters, sisters, mothers, please don't play with the health of women of all ages, children and men."

  17. As of 8/19,

    Investigation into Lupron Side Effects (Leuprolide Acetate)

    5,385 Letters and Emails Sent So Far

  18. Pfftt, this is nothing compared to the side effects of some anti-depressants, anti-psychotics, anti-smoking drugs, and a whole plethora of other medications.

  19. I wasnt aware toddlers were avid smokers and depressives.


  20. It's so strange to me how endocrinology ever got involved in psychiatry.

    Who is pushing GnRH agonists on children? They might be not completely candid, honest, and upfront about what they are doing to children, but at least they are honest about how much $$$$ is involved.

    This online article is from trans activists and an endocrinologist.

    "These agents (medicines) are both medically necessary and expensive.

    (***Yes, to being expensive, but NO to being medically necessary for a questionable psychiatric diagnosis in children.)

    Typically, Depot-Lupron costs range from around $700 (online) to $800 (Portland area) to $1,500 dollars a month elsewhere for the monthly preparation. The 3 month preparation is equivalent in price.

    (***lowest price is around $700 per** load of $$$ for pharmaceutical companies and the endocrinologists who give the drugs and monitor the kids)

    The histrelin implant is approximately $15,000 total for the device and the cost of surgically implanting it.

    Also, labs need to be monitored while on these agents. A pre-treatment LH, FSH and testosterone or estradiol level is checked, as well as a post treatment level to assess the level of suppression."

    There as numerous reasons why children, particularly teenagers, might experience psychological distress, anguish, and suicidal thoughts. This publication that was written by trans activists and an endocrinologist assumes that the ONLY reason children would exhibit such behavior is because they are "transgender". The reasons for suicidal thoughts are often complex and cumulative. As if children live in a complete cultural vacuum, no one is allowed to question the family dynamics. No, we can't do this because it's politically incorrect and taboo. For example, some parents of six or seven year old "transgender" children start calling their sons "she" or "her" at age six, and refer to their five year old daughters as "he" or "him". If a five year old girl is called "him" long enough, common sense tells us that sooner or later she is going to start believing it. Google the Washington Post video of the "transgender" five year old girl who didn't like playing with dolls, and is therefore a "boy". No wonder this kid who was branded "transgender" at age five gets horribly confused once he or she starts puberty.

    The parents have been calling this poor girl "him" ever since she was five years old, and now she starts her period. What kid wouldn't freak out?

    Any child who is different experiences stigmatization to some degree. There are numerous studies that show that adolescents who identify as gay or lesbian also suffer from depression and can be suicidal. Whether it's handicapped children, teenagers with Down Syndrome, gay teenagers, or the nerdy looking kid, adolescence is a tumultuous period, especially for anyone who is the least bit different. Since teenagers who start to notice a same sex attraction are just as stigmatized, depressed, and suicidal as transgender kids, let's start medicating gay and lesbian teenagers. Wait, they already have a cure for this. It's called "transitioning", and we know it's going on, but aren't allowed to discuss this delicate subject.


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