Change Your World-NOT your Body

Saturday, March 9, 2013

TRANSITION EQUALS DEATH!



The Male Medical Machine has long known that post menopausal women given hormone replacements were developing various cancers attributed to HRT, with breast cancer leading the pack. Unfortunately for the lives of tens of thousands of those women long since dead, studies were done confirming what those dead women already knew. Hormone Replacement Therapy causes Cancer, period! I will save my rant on the Male Gaze pressuring older women into HRT in hopes of their hanging onto a few more years of fuck-ability, fuck-ability at the risk of cancer, for another day.

Today I would like to discuss how those same synthetic hormones are causing cancer in trans women and men. I will also discuss how the Trans Politic keeps and prefers to keep that information hidden, from both the public and especially from the Trans community itself. In a recent medical article, high dosings of synthetic estrogen has been linked to breast cancer in a trans male. This man began taking transitioning hormones at age 28 and now at age 43 has an aggressive form of breast cancer. It is unknown how long his cancer has been eating away at his body, it is also unknown how many trans males and females have developed or worse, died from the long term use from the high dosing of hormones required for transition.

The homophobic medical community that created the cure for homosexuality aka transition, isnt going to warn those seeking transition about the serious dangers of these drugs anymore than it warns of the dangers of removing or rearranging healthy body parts. Their goal is to make people "normal", but as Bruce Cockburn sang "the trouble with normal is it always gets worse"! And that worse has taken root in the very community claiming to have the trans person's best interest at heart, the TRANS community itself! They would rather hang on to their Gender Straight Jacketed delusions than warn those seeking transition that transitional hormones cause cancer! Transitional hormones KILL!

We cant even guesstimate how many of our Trans Trenders transitioning in their teens will even live to see 35 or 40. If even only a third of them die from some form of cancer, that will still be literally thousands of dead females.

Fight normality. Change society, not yourself. No matter how you slice it TRANSITION EQUALS DEATH!

dirt
 
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21 comments:

  1. This is a major concern! I take very low dose hormone replacement therapy. Only because I watched all female relatives self destruct because of a horrible predisposition to osteoporosis. Not to look younger, but also because my granny was in pain for decades and lost about half her height, unable to turn over in bed for at least 5 years. I weighed the odds. We don't have a family history of breast cancer. but still, I am more suceptible to other forms of cancer, too. I would never, ever take this for any other reason. Also, I take low dose bioidentical hormones only. The drug companies are trying to do away with these. They just care about profits. They push these high doses. I pay for this out of pocket.

    Also, men do get breast cancer without hormones. There are many chemicals (plastics especially) in our water and food. These also up the risks. Rising incidence in men and women.

    To me, this taking of both female and male hormones from such young ages is really frightened. I'm glad you are writing about this.

    For women taking estrogen stopping drugs, ending up crippled for 30 years at the end of your life is a high risk. I saw it in my granny. Her mind was crystal clear, but her body destroyed. The thought of anyone choosing this route voluntarily makes me cringe. Neither men nor women should be taking high doses of these drugs.

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  2. P.S. I already had very severe osteoporosis and could not use the other drugs. I didn't take this on a whim.

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  3. I read your blog, more out of curiosity than anything. However, I feel a need to say something as someone that is (a) trans and (b) has a PhD in Epidemiology.
    Your grasp of science is rudimentary and inaccurate. The study you are citing is the Women's Health Initiative cohort study from 2002. This analysis reported a 26% increased risk of breast cancer, 29% increased risk of heart attack, and a 41% increased risk of stroke; however, there are a number of statistical issues with this paper that led to a new paper being issued in 2003 and a number of consequent critiques of the methodologies used. The authors calculated relative risks instead of absolute risk and presented unadjusted models as their results. Furthermore, after randomization (it was supposed to be a randomized trial--the gold standard of Epi studies because it controls for unmeasured statistical confounders) the women were free to either go with the randomized treatment or undergo diagnostic procedures. Diagnostic procedures resulted in 45% of women being unblinded during the trial, which means it is no longer a randomized trial, but rather an observational study. This no longer means you are controlling for unmeasured confounding. Why do we care about confounding? A perceived relationship between an independent variable (HRT) and a dependent variable (Breast cancer) can be misestimated due to the failure to account for a confounding factor leading to a spurious association. A recent Danish study, utilizing a randomized/controlled trial to HRT found no significant differences in cardiovascular or breast cancer risk between those taking HRT.
    Making the leap and generalizing results of a study of post-menopausal women from the WHI study to all trans folks is laughable. What I think we can take away from this article and what is important is that there do need to be more research studies of trans folk. Right now studies of long term hormone usage are limited to a few cohort studies from Europe. I do think that individuals should be presented with an accurate account of risks they face before opting for hormones, and at this time the data is really lacking. However, scaring folks with inaccurate representations of the scientific research is mean spirited.

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  4. Apparently you havent read it too much or you would have known the danish study has already been discussed here, in term of the exorbitant number of transitioners who go on to commit suicide AFTER taking lethal doses of fake hormones for years on end.

    Keep reading though, maybe you'll learn something beyond what men have taught you.

    dirt

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  5. The Danish study population included 1006 healthy women aged 45-58 who were recently postmenopausal or had perimenopausal symptoms in combination with recorded postmenopausal serum follicle stimulating hormone value. There is no inclusion of anyone that had transitioned. You miss my point completely. You cannot take results of a study that was designed for a specific population and generalize it to another, disparate population. That is not good science.
    If your argument is that knowledge of math and science is male taught and controlled, well then my question would be why are you using it to further your agenda?
    By the way, I am not writing this to engage with you.
    I am writing this for folks that may be questioning and scared by your presentation of inaccurate research conclusions.

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  6. Link please.

    And YOU missed the point, that women and men on syn. hormones are dying and have died as a result of those high dosing hormones. Hormones that are NOT needed whatsoever.

    They should be scared!

    Where were the studies when gay men were dropping like flies from AIDS??? They were few and fucking far between!!! BUT those in and around the gay community saw HUGE amounts of their lovers and friends and brothers dying by the dozen, didnt we?????

    There may not be the best studies out there (yet), but any gay or lesbian has seen up close and personal a high rate of heart attack, breast cancers (even after breast removal-stay tuned cuz I'll be discussing that study soon) and various other forms of cancers and suicides) by those men and women put on hormones to "cure" their MENTAL issues!!!

    dirt

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  7. I thought that the whole thing with the medical profession was to "do no harm." But then, they did this to plenty of women. High doses of birth control hormones when the pill first came out. I see this happening again here.

    Where's the research in advance of using this so freely? Then doing the research after the fact.

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  8. Research isnt done on females or minorities until the fucking bodies start piling up!

    dirt

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  9. "A rare case of breast cancer in a male-to-female transsexual raises serious questions about the scant knowledge surrounding the cancer risks of long-term cross-sex hormones, Australian and New Zealand researchers say.

    The 43-year-old patient was diagnosed with aggressive triple negative inflammatory breast cancer 15 years after she started taking cross-sex hormones, reported researchers from the University of Melbourne and the Southern Blood and Cancer Service, Dunedin.

    Prolonged exposure to hormone therapy is a known risk factor for breast cancer, and transgender patients often used hormones at much higher doses for longer periods than biological females, the authors said."

    http://www.6minutes.com.au/news/latest-news/breast-cancer-in-transsexual-patient-raises-hormon

    What I think we can take away from this article and what is important is that there do need to be more research studies of trans folk. Right now studies of long term hormone usage are limited to a few cohort studies from Europe. I do think that individuals should be presented with an accurate account of risks they face before opting for hormones, and at this time the data is really lacking. However, scaring folks with inaccurate representations of the scientific research is mean spirited.


    I don't have a Phd, but I'm not ignorant at all. I've taken biology classes at Cal which is a respected institution of higher learning. I have access to world class research facilities and libraries. Please don't assume that every person who reads Dirt's blog is illiterate or uneducated.

    Yes, I agree that there needs to be more research. I also admit that dirt has a tendency to scare people, but perhaps there is an element of truth in what she has to say. This article in question was about a transgender male and this was an aggressive type of breast cancer. As to transgender females (FTM), I'm not convinced that long term use of a synthetically produced hormone is good for anyone in the long run. History is littered with medical fads that were seen as useful, even revolutionary at one time, but turned out to be nightmares. While I don't think long term use of synthetically produced hormones is as foolhardy or as risky as thalidomide or lobotomies, no one has convinced me that it is completely safe. Doctors don't routinely give out HRT to post menopausal women like they used to.

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  10. Let's look at biological females and HRT. To state that long term use of hormones in biological females has no health risks would be inaccurate. All medications have side effects. Indeed, there are no drugs that do not have side effects. I'm assuming that the American Cancer Society has updated information.

    http://www.cancer.org/cancer/cancercauses/othercarcinogens/medicaltreatments/menopausal-hormone-replacement-therapy-and-cancer-risk

    Hormone therapy and breast cancer risk

    Estrogen-progestin therapy (EPT) and breast cancer risk

    Results from the Women’s Health Initiative (WHI) have shown that daily use of EPT raises women’s risk of developing breast cancer when compared to those who don’t take hormones. To put this into numbers, if 10,000 women took EPT for a year, this would add up to about 8 more cases of breast cancer per year than if they had not taken any hormone therapy (HT). The longer HT was used, the more the risk increased.

    In this study, women who took EPT also had a higher risk of having breast cancer found at a more advanced stage and were more likely to have breast density changes seen on mammograms. Lean women or women with dense breasts who take EPT may be at particularly high risk of breast cancer.

    Risk of breast cancer from EPT applies only to current and recent users. Breast cancer risk is thought to decrease after stopping HT. The risk returns to that of women who never used HT (the usual risk) within 3 years of stopping.

    Women who have had hysterectomies can take estrogen therapy (ET) instead of EPT. These women do not need progestin to protect against uterine cancer, and they are increasing their risk of breast cancer by taking EPT.

    Estrogen therapy (ET) and breast cancer risk

    Part of the Women’s Health Initiative (WHI) looked at women who no longer had a uterus, and whose ovaries were either removed or had stopped working. Those who were taking ET had a slightly lower risk of breast cancer.

    The British “Million Women Study,” and many other studies like this, reported a very slight increase in breast cancer risk (about 1% to 3% increase per each year of use) among women who took ET, compared to women who took the placebo.

    Hormone therapy and ovarian cancer risk

    Ovarian cancer is rare, which makes it harder to study its risk factors. Even when something increases the relative risk of developing ovarian cancer, the risk of actually getting this cancer is still likely to be low.

    But there are no good screening tools for ovarian cancer and it’s often fatal, so even the small risk linked to hormone therapy (HT) may be worth considering.

    Estrogen-progestin therapy (EPT) and ovarian cancer risk

    It’s still not known for certain if hormone therapy (HT) increases the risk of ovarian cancer. If it does increase risk, it increases it only slightly.

    The Women’s Health Initiative (WHI) found that continuous EPT may increase the risk of ovarian cancer a bit. But this finding may have been due to chance because of the small number of women who developed ovarian cancer during the study. Other studies also suggest that EPT may increase risk slightly, but less than estrogen therapy (ET) does.

    Estrogen therapy (ET) and ovarian cancer risk

    Studies have shown that women who take ET have a higher risk for ovarian cancer compared with women who take no hormones after menopause. The risk of ovarian cancer increases the longer a woman uses ET.

    The largest study so far found that women who had used ET for 5 or more years had about a 50% increased risk of developing ovarian cancer. This link was confirmed in another large study. The risk of ovarian cancer appeared to increase further the longer was used.

    Hormone therapy and risk of other cancers

    Hormone therapy may play a role in other cancers, such as lung cancer and melanoma. There is not enough evidence to determine any effect at this time.

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  11. The person with the Phd automatically assumes that ALL FTMs have their testosterone levels properly monitored on a routine basis. The female body converts excess testosterone to estrogen.

    Susan G. Komen....excellent source of information on breast cancer

    "Introduction: Androgens (such as testosterone) are natural hormones. They are important in sexual development in both men and women. In women, androgens are produced in small amounts by the ovaries and the adrenal glands. Similar to higher blood estrogen levels, higher amounts of androgens in the blood may be linked to an increased risk of breast cancer in women.

    Testosterone

    Of the androgens that have been studied in relation to breast cancer risk, the most data are available for testosterone. Studies show higher blood levels of testosterone may increase the risk of breast cancer in postmenopausal women. And, although findings are limited, there is some evidence that higher blood levels of testosterone may also increase breast cancer risk in premenopausal women. "


    http://ww5.komen.org/ContentNoSidebar.aspx?id=6442451098&terms=testosterone

    Females naturally produce very small amounts of testosterone. Getting the right dosage of testosterone is tricky in FTMs because the female body converts excess testosterone to estrogen. Is any synthetically produced hormone beneficial to women if taken for decades, especially menopausal women?

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  12. PCOS - Please don't tell me that this isn't an issue for FTMs.

    Even transgender sources are familiar with the issue of PCOS (polycystic ovarian syndrome) and testosterone

    "Why have a hysterectomy/oophorectomy?
    Some physicians recommend hysterectomy and oophorectomy within the first 5 years of starting testosterone therapy. There are two reasons for this. First, there is some concern that long-term testosterone treatment may cause the ovaries to develop similar symptoms as those seen in polycystic ovarian syndrome (PCOS). PCOS has been linked to increased risk of endometrial hyperplasia (a condition that occurs when the lining of the uterus (endometrium) grows too much) and thus endometrial cancer, as well as ovarian cancer.

    The second reason why it may be considered beneficial to undergo a hysto/oopho is that after the removal of the ovaries, testosterone doses can often be decreased because the ovaries are no longer producing estrogen.

    If a trans man chooses not to have a hysto/oopho procedure, he should continue to have regular Pap smears (to screen for cervical cancer) and should seek out the care of a doctor if he experiences any irregular vaginal bleeding (including spotting), cramping, or pain. It is not uncommon for trans men who are pre-hysterectomy to experience a buildup of endometrial tissue, especially during the first few years of testosterone therapy. Endometrial tissue is normally shed during menstruation, but since this process is usually stopped a few months into testosterone therapy, additional tissue may continue to build up and may eventually begin to shed in the form of spotting. Because irregular bleeding can be a sign of cancer (though this is often not the case), trans men who experience any bleeding/spotting should see a doctor who will perform tests to determine the cause of the spotting. These tests may include an endometrial biopsy and/or an ultrasound. The doctor may advise a short course of progesterone to cause the uterus to shed the excess endometrial tissue-- this is much like inducing a period. While this may be unpleasant, it should be understood as a preventative measure, since the unusual buildup of endometrial tissue has been linked to endometrial cancer."

    http://www.ftmguide.org/hysto.html#why

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  13. Trans females still need gynocological screening if they still have their ovaries and uterus. After all, they are still female.

    "Osteoporosis has been reported in both older transmen and transwomen, and is frequently associated with poor compliance with the hormone regimen. (Grade B)

    Some patients prefer to stop hormonal therapy; for post-gonadectomy patients under age 50, this is not recommended due to bone loss, and potential symptoms similar to menopause in both transwomen and transmen. (Grade A, B, C)
    •Transmen without hysterectomy: Pelvic exams every 1-3 years for patients over age 40 or with a family history of uterine or ovarian cancer; increase to every year if polycystic ovarian syndrome (PCOS) (see MedlinePlus) is present. Consider hysterectomy and oophorectomy if the patient's health will not be adversely affected by surgery, or if the patient is unable to tolerate pelvic exams. (Grade B, C)
    •Transmen: Consider bone density screening if age > 60 and if taking testosterone for < 5-10 years; if taking testosterone for > 5-10 years, consider at age 50+, earlier if additional risk factors for osteoporosis are present; recommend supplemental calcium and vitamin D in accordance with current osteoporosis prevention guidelines to help maintain bone density. Note that this may be applied to transmen at ages younger than typical starting age for osteoporosis prevention treatment due to the unknown effect of testosterone on bone density. (Grade B, C)

    Transmen stopping testosterone will experience loss of libido, hot flashes, loss of body hair, muscle tone, and weight redistribution in a female pattern. (Grade C)"

    http://transhealth.ucsf.edu/trans?page=protocol-aging

    "RESULTS:

    Of the 69 participating FTM cases, 40 (58.0%) were found to have PCOS. Of the 49 for whom HOMA-IR was calculated, 15 (30.6%) also showed insulin resistance, whereas of the 59 for whom adiponectin was measured, 18 (30.5%) showed hypoadiponectinaemia. Of 69 for whom androgens were measured, 29 (39.1%) showed hyperandrogenaemia. Insulin resistance was associated with obesity but not with PCOS. In contrast, hyperandrogenaemia was associated with both PCOS and obesity.

    CONCLUSION:

    FTM transsexual patients have a high prevalence of PCOS and hyperandrogenaemia."

    http://www.ncbi.nlm.nih.gov/pubmed/17166864

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  14. You cannot take results of a study that was designed for a specific population and generalize it to another, disparate population. That is not good science.

    Biological males are still biological males. Biological females are still biological females. Isn't it true that the vast majority of transsexuals are either biological males or biological females who do NOT have an intersex medical condition.

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  15. A recent Danish study, utilizing a randomized/controlled trial to HRT found no significant differences in cardiovascular or breast cancer risk between those taking HRT.

    Please list the source instead of saying "a recent Danish study".

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  16. Don't forget that there are other risks. I think the reason that they stopped the WHI study early and took most women off hormone replacement was not due to cancer.

    It was due to an increased risk of cardiovascular-related deaths. The higher the dose, the greater the risk. More people die or become disabled due to cardio problems than reproductive cancers. So, it's another risk that should be seriously considered.

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  17. Cardio includes stroke as well as heart attacks.

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  18. *I AM NOT A PHYSICIAN
    *DIRT IS NOT A PHYSICIAN
    *THE PERSON WHO SAYS HE OR SHE HAS A PhD. IN EPIDEMIOLOGY IS NOT A PHYSICIAN EITHER.

    If people are interested, below is a link from the Annals of Internal Medicine.

    Annals of Internal Medicine

    Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: U.S. Preventive Services Task Force Recommendation Statement

    January 2013

    http://annals.org/article.aspx?articleid=1384872


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  19. Anything you put in your body can cause cancer. This is just another excuse for you to nit pick the trans community. Worry about yourself and ALL of your mental problems.

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  20. No, some things are known to carry an increased risk of cancer. Like asbestos, for instance. It was once thought to be safe, or pooh-poohed as you are doing here. Some things carry a greater risk, or a much greater risk. That's why doctors have to prescribe it, rather than it being over the counter.

    That is why a doctor would be concerned about hormone therapy, for instance. Plus, it is the risk for cardio that is even greater. This is based on a huge research study. It's not that anything can cause it.

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  21. Uhm "I read your blog, more out of curiosity than anything. However, I feel a need to say something as someone that is (a) trans and (b) has a PhD in Epidemiology. " I for one am not impressed. And as expected you throw out the research that only the trans community does not find questionable at best. Your life your choice but hormones long term very well may kill.
    Check the new stats out on a rare and fast growing breast cancer in M2T--Swedish Study. You are correct can't leap from menopausal or post women to men. It will kill men a whole lot faster. People can't be presented with the risks until they are know. You are the canary in the cave--good luck.

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